Chinese Name: DRAQ7 Dye

English Name: DRAQ7 Dye

Abbreviation: DRAQ7 Dye

CAS Number: 1533453-55-2

Molecular Formula: NA

Molecular Weight: NA

Specifications: 1 mg / 5 mg / 10 mg (Custom packaging supported)

Form: Lyophilized powder

Product Number: G10040033

Stock: In stock

Color: Far-red fluorescence

DRAQ7 is a charged anthraquinone derivative that cannot penetrate the intact plasma membrane of live cells – this "gate" separates live cells from the outside, and DRAQ7 is kept out. When cells undergo apoptosis, necrosis, or membrane damage, the "gate" is breached, allowing DRAQ7 to enter the nucleus and intercalate into the double helix structure of double-stranded DNA. Upon intercalation, the fluorescence is significantly enhanced, emitting far-red light with an emission wavelength of 694-697 nm.

A simple three-step logic chain: Structure (membrane-impermeable anthraquinone) → Event (membrane damage allows entry) → Signal (fluorescence turns on upon DNA intercalation). This mechanism ensures that only dead or membrane-damaged cells are labeled.

• Dead Cell Exclusion in Flow Cytometry: Used to accurately exclude dead cell populations in multicolor immunophenotyping or cell cycle analysis, avoiding non-specific staining and autofluorescence interference in data gating.

• Cell Viability Assessment and Apoptosis Detection: Used in combination with apoptosis markers such as Annexin V to distinguish live cells, early apoptotic cells, and late apoptotic/necrotic cells.

• Real-time Live-Cell Death Monitoring: Used in siRNA studies or long-term imaging experiments to dynamically record the entire cell death process; the low toxicity of the dye ensures that the signal truly reflects the cell state.

✅ High Cost-Effectiveness

Exclusively developed and produced domestically, offering significant price advantages compared to similar imported products, and supporting stable supply and batch-to-batch consistency, effectively reducing long-term experiment and project development costs.

✅ Low Toxicity

At effective working concentrations, it does not induce DNA damage or affect cell function, avoiding artifacts caused by dye toxicity and ensuring the authenticity of experimental data.

✅ Long-term Incubation Capability

No need to "stain and measure immediately"; it can be directly added to the culture system and "left in" without affecting the proliferation and function of live cells, suitable for continuous experiments.

✅ Real-time Monitoring Capability

This dye can track the cell death process in real time. Compared with traditional endpoint detection methods, DRAQ7 provides dynamic cell state data, yielding more accurate results.